Diversions are in place at Farndon roundabout. Drivers are told to expect delays until at least midday.
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Register freeThe A46 is closed in both directions near Farndon roundabout after a lorry overturned at around 3am.
Police say the driver was taken to hospital with injuries that are not thought to be life-threatening.
Recovery crews are working to clear the carriageway. Drivers should avoid the area and allow extra time this morning.
We will update this story as the road reopens.
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